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ABL Bio signs licensing-out agreement with TRIGR Therapeutics
  • By Lee Han-soo
  • Published 2018.12.03 14:26
  • Updated 2018.12.03 14:26
  • comments 0

ABL Bio said Friday that it has licensed out ABL001, a bispecific antibody with indications for anti-cancer and eye treatment, to TRIGR Therapeutics, a U.S. no research and development only (NRDO) company.

Under the accord, ABL Bio will transfer the exclusive license rights for ABL001 to TRIGR Therapeutics, which will pay $595 million, including a $5 million contract fee.

TRIGR Therapeutics will also gain exclusive global rights to the drug candidate except for Korea and Japan.

ABL001, one of ABL Bio’s main pipelines, is a bispecific antibody that binds simultaneously to VEGF (vascular endothelial growth factor) and delta-like ligand 4 (DLL4), which play an essential role in the neovascularization process.

It has a high binding force to each antigen and has a structure that receives fewer structural interference when the antigen and antibody bind, which in turn, result in a high therapeutic effect.

The company is currently conducting phase I clinical trials for the drug.

“The technology transfer agreement is the company's fifth technology transfer contract and the fourth contract this year,” ABL Bio CEO Lee Sang-hoon said. “Such a feat demonstrates that more and more pharmaceutical companies are recognizing our technology.”

The company will continue to lead the field of dual antibody-based drug development through continuous research and development, he added.


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